Hello there,
There are a lot of options as stated previously.
Personally, I like Joomla because it works great whether you know HTML, PHP coding, etc or just know how to use WYSIWYG (which Joomla includes).
If you are a beginner the new Joomla 1.5 is probably the best for you. I like the other version, because I like to edit the code personally.
The main reason I like Joomla, is because it's an Open-Source program, meaning it's not meant for the developers to get rich off it. There is always a lot of help available, and there are people who design editable templates for fun. Actually,
http://www.siteground.com/ includes hundreds of templates for free whether you sign up with them or not.
You said you have your domain parked, but if you don't have a hosting plan, siteground.com is the best for Joomla because they install it automatically for you with included templates that you can easily edit.
I know I'm rambling, but Joomla has helped me learn a lot about designing websites. There are also a lot of extensions and modules that you can install for your website, like Calendars, blogging, chat rooms, and much more for free.
I like Dreamweaver, though, with many Adobe applications they seem a little costly for me and takes a while to learn all of the in and outs.
If you are curious about HTML learning,
http://w3schools.com/ is the best free source for tutorial on learning HTML, PHP, ASP, etc etc.
Anyway, I would love to help if you have anymore questions.
-Jeremy