It depends on the site I guess. I tried AdBrite's inline ad service for about a day on the site but I hated how it interfered with the text. To me it looked sort of cheesy. One thing I don't like about them is you can't really control how many words get linked so you could have an article with 20 or so inlinks and to me it looks distracting.
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Don't put the cart before the horse. Plan your website, thencreate it.
Same with the inline ads publisher I'm using which is Kontera (http://kontera.com). If the page is small it will only put one or two ads (if any). But as the page get's more and more content, the more that gets underlined. I don't know if there is an upper limit to how many in line ads show up but I hear in text advertising can have good payouts if you have a good niche.
How do you feel about Contextual inline text link ads?
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