I'm not really sure there's much you can do to combat that since you have no control over what ads show up. Different ads are going to convert differently on different sites. Say you have a site on something very rare like Mongolian monkeys (LOL). I would image the ads would not be as targeted as if you had something like "MySpace Layouts". So obviously the Mongolian site is going to be hurt more by the smart pricing simply because their content is not as targeted to the ads.
So I'm not really sure there's anything you can do since you don't control what ads show up on your pages.
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