I've always been a left nav kinda gal. I've never tried anything but that. I've also noticed that with my 3 column site, the ads and links on the left get way more clicks than the ones on the right. No surprise though. As TechieGuy says, people tend to read left to right.

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Don't put the cart before the horse.
Plan your website, then create it.

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2 Create a Website | 2 Create a Website Blog
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Recent Blog Posts...

Lisa's Favorite Web Tools & Websites
Stop The SEO Madness! [Video]
My Thoughts on Lazy People